Product Name:Doxorubicin hydrochloride
CAS: 25316-40-9
Molecular Formula: C27H30ClNO11
MW:Â 579.98
EINECS:Â 246-818-3
Purity (HPLC): 99%
Packing: 2mg/vial
Appearance: White powder
Grade:Pharmarceutical Grade
Description:
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
It is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
Application:
Â
1 Hodgkin's disease and lymphosarcoma, reticulum cell sarcoma.Â
2 Undifferentiated small cell and non-small cell lung cancer, breast cancer.Â
3 Acute lymphoblastic and myeloid leukemia.Â
4 Osteosarcoma and soft tissue sarcoma.Â
5 Ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.Â
Uses:
1.Used as an antineoplastic
2.Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent.
3.Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications.Â
Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
4.Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.
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The quality control process:
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before sellingÂ
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Our Advantages:
1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years.Â
2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .
3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.
4. Fast delivery: We have stock, so we can delivery quickly once payment is received.
5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.
6. Competitive prices: A discount would be given when you make a large order.
Â
| Make an order | Please make clear what product and what quantity you need |
| Quote | Prices and Specifications details would be offered for you to consider and confirm |
| Payment ways | Bank Transfer, Western Union, Money Gram and Bitcoin |
| Delivery ways | All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
| Shipping address | Provide your Valid and Correct destination address info(if possible with post code, phone number). |
| Packing | Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
| Lead time | Within 8 hours upon receipt of payment |
| Package picture | Photos of package would be offered to tell apart the items |
| Tracking number | Offered once it is released |
| Shipping time | 3-7 working days (Door-to-Door) |
| After-sale service | 24/7 Online for any problems |
 99% Factory Direct Antineoplastic Raw Powder Doxorubicin Hydrochloride CAS 25316-40-9
Product Name:Doxorubicin hydrochloride
CAS: 25316-40-9
Molecular Formula: C27H30ClNO11
MW:Â 579.98
EINECS:Â 246-818-3
Purity (HPLC): 99%
Packing: 2mg/vial
Appearance: White powder
Grade:Pharmarceutical Grade
Description:
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
It is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, with the most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
Application:
Â
1 Hodgkin's disease and lymphosarcoma, reticulum cell sarcoma.Â
2 Undifferentiated small cell and non-small cell lung cancer, breast cancer.Â
3 Acute lymphoblastic and myeloid leukemia.Â
4 Osteosarcoma and soft tissue sarcoma.Â
5 Ovarian cancer, testicular cancer, bladder cancer, . Wilms cancer, prostate cancer, thyroid cancer, neuroblastoma cancer, esophageal cancer, stomach cancer, liver cancer, cervical cancer and head and neck cancer. Multiple myeloma, pancreatic cancer, endometrial cancer and brain tumors can also be applied.Â
Uses:
1.Used as an antineoplastic
2.Strong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent.
3.Doxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications.Â
Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
4.Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.
Â
The quality control process:
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before sellingÂ
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Our Advantages:
1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years.Â
2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .
3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.
4. Fast delivery: We have stock, so we can delivery quickly once payment is received.
5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.
6. Competitive prices: A discount would be given when you make a large order.
Â
| Make an order | Please make clear what product and what quantity you need |
| Quote | Prices and Specifications details would be offered for you to consider and confirm |
| Payment ways | Bank Transfer, Western Union, Money Gram and Bitcoin |
| Delivery ways | All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
| Shipping address | Provide your Valid and Correct destination address info(if possible with post code, phone number). |
| Packing | Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
| Lead time | Within 8 hours upon receipt of payment |
| Package picture | Photos of package would be offered to tell apart the items |
| Tracking number | Offered once it is released |
| Shipping time | 3-7 working days (Door-to-Door) |
| After-sale service | 24/7 Online for any problems |
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Ganoderma extract (Ganoderma Lucidum
extract/Reishi Mushroom Extract) is extracted from top-graded organic
shell-broken Ganoderma Lucidum spore powder using advanced modern technology. Spores
are the seeds of Ganoderma Lucidum. When it matures, the spores are released
from the mushroom cap. They are also where most of the nutrients of Ganoderma
Lucidum are contained. In order to allow the nutrients inside the spore powder
to be fully absorbed by human body, we used a patented technology called low
temperature physical shell-breaking technology to crack the cell wall of
Ganoderma Lucidum spore powder.
The Ganoderma we used for this product comes from our self-built organic Ganoderma farm at Mt. Wuyi. Both the farm and the GMP workshop have acquired organic certifications from 4 countries and regions including Chinese, Japan, the US, and the EU. We do not use any type of herbicide, pesticide, or chemical fertilizer during the whole cultivation process, delivering the best and safest product to our customers.
By using extraction technology, we can increase the concentration of Ganoderma polysaccharides and triterpenes in the product. Reishi Mushroom Powder polysaccharides and triterpenes both work together to enhance human`s immune system, fighting against diseases and infections. Also, Ganoderma can help protect the liver, increase sleep quality as well as relive stress.
Ganoderma Extract
Ganoderma Extract,Reishi Mushroom Extract,Organic Ganoderma Extract,Ganoderma Lucidum Powder
Ganoherb International Inc , http://www.ganoherb.com