Model NO.: 186826-86-8
CAS: 186826-86-8
Appearance: Light Yellow Powder
Trademark: YCGC
Transport Package: Foil Bag
Specification: 10g
Origin: China
HS Code: 1234577
Model NO.: 186826-86-8
CAS: 186826-86-8
Appearance: Light Yellow Powder
Trademark: YCGC
Transport Package: Foil Bag
Specification: 10g
Origin: China
HS Code: 1234577
Basic Info.Synonyms: AVALOX;BAY-12-8039;(1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO- 8-METHOXY-7- [(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;1-CYCLOPROPYL-7-[(S,S)-2,8-DIAZA-BICYCLO[4.3.0]NON-8-YL]-6-FLUORO-8-METHOXY-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID HYDROCHLORIDE;ACTIRA;PROFLOX;MOXIFLOXACIN HCL
CAS: 186826-86-8
MF: C21H25ClFN3O4
MW: 437.89
Appearance: light yellow powder
Usage acetylcholinesterase inhibitor (reversible), cognitive enhancer
Description
Moxifloxacin hydrochloride is a broad spectrum and antimicrobial activity of 8- methoxy quinolone antibacterial drug .In vitro showed against gram positive bacteria, gram negative bacteria, anaerobic bacteria, acid fast bacteria and atypical organisms such as Mycoplasma, chlamydia and Legionella have broad-spectrum antibacterial activity.
Moxifloxacin hydrochloride antibacterial mechanism for the interference of II, IV topoisomerase. Topoisomerase is to control the DNA topology and in DNA replication, repair and transcription of key enzyme.
Moxifloxacin hydrochloride bactericidal curves show, moxifloxacin hydrochloride is a concentration dependent bactericidal activity. Minimum bactericidal concentration and minimum inhibitory concentration is consistent. Moxifloxacin hydrochloride on b- lactam and a macrolide antibiotic resistant bacteria are effective.
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COA
| TEST | SPECIFICATION | RESULT |
| Appearance | Light yellow or yellow powder | A light yellow powder |
| Solution | Lightly soluble in water, hardly soluble in ethanol, not soluble in acetone. | Conform |
| Identification | A: IR | Conform |
| B: The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | Conform | |
| C: To a solution (1 in 160) add diluted nitric acid, and filter. The filtrate meets the requirements of the tests for Chlorides 191. | Conform | |
| Specific Rotation | Between -125° and -138° | -130.2° |
| pH | 3.9 ~ 4.6 | 4.2 |
| Residue on ignition | Not more than 0.1% | 0.04% |
| Water | Not more than 1.0% | 0.4% |
| Heavy metal | 10ppm max. | Conform |
| Related compounds | Impurity A: ≤0.1% | 0.04% |
| Impurity B: ≤0.1% | 0.03% | |
| Impurity C: ≤0.1% | 0.04% | |
| Impurity D: ≤0.1% | 0.02% | |
| Impurity E: ≤0.1% | 0.02% | |
| Other individual impurity: ≤0.1% | 0.03% | |
| Total impurities: ≤0.5% | 0.21% | |
| Residue solvents | DMF: 0.088% Max. | Conform |
| Triethylamine: 0.5% Max. | No dected | |
| Acetone: 0.5% Max. | No dected | |
| Methanol: 0.3% Max. | Conform | |
| Ethanol: 0.5% Max. | No dected | |
| Microbial limits test | Total aerobic microbial count ≤ 1000cfu/g Total combined molds and yeasts count ≤ 100cfu/g |
Conform  Conform |
| Assay | 98.0 ~ 102.0% (anhydrous basis) | 100.2% |
| Storage | Airtight, not have light, in room temperature. | |
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Our advantage
a.Rich experience.We are a professional manufacturer in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
b.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
c.Safe and fast delivery.We will send you with a safest and most suitable channel.
d.Good after-sales service.Our purpose is to hold a long friendly cooperation with our customers,so we will offer you best service from start to finish.
 Basic Info.
Synonyms: AVALOX;BAY-12-8039;(1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO- 8-METHOXY-7- [(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;1-CYCLOPROPYL-7-[(S,S)-2,8-DIAZA-BICYCLO[4.3.0]NON-8-YL]-6-FLUORO-8-METHOXY-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID HYDROCHLORIDE;ACTIRA;PROFLOX;MOXIFLOXACIN HCL
CAS: 186826-86-8
MF: C21H25ClFN3O4
MW: 437.89
Appearance: light yellow powder
Usage acetylcholinesterase inhibitor (reversible), cognitive enhancer
Description
Moxifloxacin hydrochloride is a broad spectrum and antimicrobial activity of 8- methoxy quinolone antibacterial drug .In vitro showed against gram positive bacteria, gram negative bacteria, anaerobic bacteria, acid fast bacteria and atypical organisms such as Mycoplasma, chlamydia and Legionella have broad-spectrum antibacterial activity.
Moxifloxacin hydrochloride antibacterial mechanism for the interference of II, IV topoisomerase. Topoisomerase is to control the DNA topology and in DNA replication, repair and transcription of key enzyme.
Moxifloxacin hydrochloride bactericidal curves show, moxifloxacin hydrochloride is a concentration dependent bactericidal activity. Minimum bactericidal concentration and minimum inhibitory concentration is consistent. Moxifloxacin hydrochloride on b- lactam and a macrolide antibiotic resistant bacteria are effective.
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COA
| TEST | SPECIFICATION | RESULT |
| Appearance | Light yellow or yellow powder | A light yellow powder |
| Solution | Lightly soluble in water, hardly soluble in ethanol, not soluble in acetone. | Conform |
| Identification | A: IR | Conform |
| B: The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | Conform | |
| C: To a solution (1 in 160) add diluted nitric acid, and filter. The filtrate meets the requirements of the tests for Chlorides 191. | Conform | |
| Specific Rotation | Between -125° and -138° | -130.2° |
| pH | 3.9 ~ 4.6 | 4.2 |
| Residue on ignition | Not more than 0.1% | 0.04% |
| Water | Not more than 1.0% | 0.4% |
| Heavy metal | 10ppm max. | Conform |
| Related compounds | Impurity A: ≤0.1% | 0.04% |
| Impurity B: ≤0.1% | 0.03% | |
| Impurity C: ≤0.1% | 0.04% | |
| Impurity D: ≤0.1% | 0.02% | |
| Impurity E: ≤0.1% | 0.02% | |
| Other individual impurity: ≤0.1% | 0.03% | |
| Total impurities: ≤0.5% | 0.21% | |
| Residue solvents | DMF: 0.088% Max. | Conform |
| Triethylamine: 0.5% Max. | No dected | |
| Acetone: 0.5% Max. | No dected | |
| Methanol: 0.3% Max. | Conform | |
| Ethanol: 0.5% Max. | No dected | |
| Microbial limits test | Total aerobic microbial count ≤ 1000cfu/g Total combined molds and yeasts count ≤ 100cfu/g |
Conform  Conform |
| Assay | 98.0 ~ 102.0% (anhydrous basis) | 100.2% |
| Storage | Airtight, not have light, in room temperature. | |
    Â
Our advantage
a.Rich experience.We are a professional manufacturer in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
b.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
c.Safe and fast delivery.We will send you with a safest and most suitable channel.
d.Good after-sales service.Our purpose is to hold a long friendly cooperation with our customers,so we will offer you best service from start to finish.
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