Factory Supply Natural Peanut Shell Extract 80%; 98%Luteolin HPLC

 Peanut Shell Extract



Plant Origin: Arachis hypogaea
Part Used: Shell
Specification: Luteolin 80%, 90%, 95%, 98% by HPLC
CAS No.: 491-70-3
Molecular Formula: C15H10O6
Molecular Weight: 286.24
Appearance: Yellow to light green powder
Molecular Stucture:
Indications: 
Luteolin is a naturally occurring compound found in foods including peanut shell, parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others.
Luteolin has antioxidant, anti-inflammatory, anti-allergic, anticancer, and immune-modulating properties to suppress hyperactive immune systems. Luteolin is a potent hypoglycemic agent and improves insulin sensitivity. Luteolin may help promote healthy blood glucose levels and help in weight management for Syndrome X.
 



Main Function:
1) Luteolin Fights Cancer
It inhibits the growth of new blood vessels in tumors, the metabolism of carcinogens, as well as stopping the progression of the cell cycle in cancer cells. Luteolin also induces cell death in cancer cells.
 
In mice, luteolin suppressed growth of tumors formed from human skin carcinoma, hepatoma, and human ovarian cancer cells.
 
Luteolin inhibited the incidence rate of tumors and decreased the size of tumors significantly.
 
Long term treatment did not show any apparent toxicity in rats at a dose of 30mg/kg, implying that luteolin is relatively safe as an anticancer agent.
 
Through in vitro and vivo experiments, luteolin was found to have therapeutic and preventative activities against cancer associated with estrogen.
 
2) Luteolin Decreases Inflammation
 
Experiments with animals show that luteolin suppresses bacteria-induced inflammation.
 
Luteolin is also found to suppress two major pathways involved in response to inflammation, which greatly reduces both acute and chronic inflammation.
 
Luteolin suppressed pro-inflammatory marker expression and cytokine expression in LPS-activated microglia.
 
In an experiment on rats with toxin-induced uveitis, luteolin had great success in anti-inflammatory treatment, comparable to that of prednisolone.
 
3) Luteolin is an Antioxidant
 
Luteolin is an oxygen scavenger. It was found to inhibit reactive oxygen species, which induce damage of lipids, DNA, and protein.
 
Luteolin significantly induces genes related to antioxidant defense.
 
4) Luteolin is a Natural Sun Protectant
 
Luteolin potently inhibited UVB-induced MMP-1 expression and wrinkle formation in vitro and in vivo and therefore may be used for prevention of UVB-induced skin aging.
 
5) Luteolin Improves Heart Function
 
In an experiment on rats, luteolin was found to inhibit cell death in the cells of the heart. This suggest that luteolin can be used in the prevention and treatment of cardiovascular diseases.
 
Luteolin substantially increased cell life while reducing evidence of oxidative stress-induced damage in the cells.
 
Luteolin also improved the recovery of heart cells contracting function following simulated injury caused by loss of blood flow, by reducing oxidative stress.
Get SelfHackeds 7 day email crash course on optimal living for free. Includes detailed and cited tips on stress, sleep, fatigue, weight loss, brain fog and more!
 
6) Luteolin Protects the Brain From Neurological Impairments
 
Luteolin treatment in rats reduced brain damage caused by kainic acid by reducing glutamate levels, mitigating inflammation, and enhancing the hippocampus.
 
Tests on flies expressing a neurological impairment that resembles amyloidosis showed that luteolin rescued the impairment.
 
Luteolin induces neurite outgrowth through CREB activation. CREB activation is the mechanism underlying its effects on memory enhancement.
 
Luteolin can go through the blood-brain-barrier (BBB), which shows anti-amnesic effects against the toxicity of amyloid in mice.
 
In an experiment on rats with streptozotocin induced Alzheimer's disease, luteolin significantly improved spatial learning and memory impairment.
 
Luteolin also protects against high-fat diet-induced cognitive defects in obesity mice.
 
7) Luteolin is an Antiviral
 
Autoimmunity
 
Luteolin was found to have potent antiviral activity against Japanese encephalitis virus (JEV).
 
Luteolin reduced the number of Epstein-Barr virus reactivating cells and reduced the production of the virus. It does this by repressing the activities of the promoters of the immediate-early genes Zta and Rta.   
 
In mice with hepatitis B virus (HBV), Luteolin reduced HBV DNA replication, suggesting that it may be used for anti-HBV therapy.
 
8) Luteolin Prevents Cataracts
 
In rats, luteolin enhanced the antioxidant potential and lowered the oxidative damage to the lens' of rats in selenite-induced cataracts. It also improved the membrane integrity of the lens.
 
9) Luteolin May Be Therapeutic for Multiple Sclerosis
 
Multiple Sclerosis is a disease that affects the immune system - nerve damage causes pain and fatigue. Luteolin has anti-oxidant and anti-inflammatory effects which can reduce the effects of multiple sclerosis .
 
10) Luteolin Inhibits Mast Cells
 
Luteolin inhibits mast cells and mast cell-dependent T cell activation, factors which contribute to multiple sclerosis .
 
In this way, it can also help with histamine intolerance.
 
11) Luteolin Has Anti-Depressant Effects
 
The endoplasmic reticulum in a cell can undergo stress, which can cause cell death. In the brain, neuronal cells undergo cell death and this can cause symptoms of depression.
 
Luteolin significantly suppresses cell death by relieving endoplasmic reticulum stress.






 

 Peanut Shell Extract



Plant Origin: Arachis hypogaea
Part Used: Shell
Specification: Luteolin 80%, 90%, 95%, 98% by HPLC
CAS No.: 491-70-3
Molecular Formula: C15H10O6
Molecular Weight: 286.24
Appearance: Yellow to light green powder
Molecular Stucture:
Indications: 
Luteolin is a naturally occurring compound found in foods including peanut shell, parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others.
Luteolin has antioxidant, anti-inflammatory, anti-allergic, anticancer, and immune-modulating properties to suppress hyperactive immune systems. Luteolin is a potent hypoglycemic agent and improves insulin sensitivity. Luteolin may help promote healthy blood glucose levels and help in weight management for Syndrome X.
 



Main Function:
1) Luteolin Fights Cancer
It inhibits the growth of new blood vessels in tumors, the metabolism of carcinogens, as well as stopping the progression of the cell cycle in cancer cells. Luteolin also induces cell death in cancer cells.
 
In mice, luteolin suppressed growth of tumors formed from human skin carcinoma, hepatoma, and human ovarian cancer cells.
 
Luteolin inhibited the incidence rate of tumors and decreased the size of tumors significantly.
 
Long term treatment did not show any apparent toxicity in rats at a dose of 30mg/kg, implying that luteolin is relatively safe as an anticancer agent.
 
Through in vitro and vivo experiments, luteolin was found to have therapeutic and preventative activities against cancer associated with estrogen.
 
2) Luteolin Decreases Inflammation
 
Experiments with animals show that luteolin suppresses bacteria-induced inflammation.
 
Luteolin is also found to suppress two major pathways involved in response to inflammation, which greatly reduces both acute and chronic inflammation.
 
Luteolin suppressed pro-inflammatory marker expression and cytokine expression in LPS-activated microglia.
 
In an experiment on rats with toxin-induced uveitis, luteolin had great success in anti-inflammatory treatment, comparable to that of prednisolone.
 
3) Luteolin is an Antioxidant
 
Luteolin is an oxygen scavenger. It was found to inhibit reactive oxygen species, which induce damage of lipids, DNA, and protein.
 
Luteolin significantly induces genes related to antioxidant defense.
 
4) Luteolin is a Natural Sun Protectant
 
Luteolin potently inhibited UVB-induced MMP-1 expression and wrinkle formation in vitro and in vivo and therefore may be used for prevention of UVB-induced skin aging.
 
5) Luteolin Improves Heart Function
 
In an experiment on rats, luteolin was found to inhibit cell death in the cells of the heart. This suggest that luteolin can be used in the prevention and treatment of cardiovascular diseases.
 
Luteolin substantially increased cell life while reducing evidence of oxidative stress-induced damage in the cells.
 
Luteolin also improved the recovery of heart cells contracting function following simulated injury caused by loss of blood flow, by reducing oxidative stress.
Get SelfHackeds 7 day email crash course on optimal living for free. Includes detailed and cited tips on stress, sleep, fatigue, weight loss, brain fog and more!
 
6) Luteolin Protects the Brain From Neurological Impairments
 
Luteolin treatment in rats reduced brain damage caused by kainic acid by reducing glutamate levels, mitigating inflammation, and enhancing the hippocampus.
 
Tests on flies expressing a neurological impairment that resembles amyloidosis showed that luteolin rescued the impairment.
 
Luteolin induces neurite outgrowth through CREB activation. CREB activation is the mechanism underlying its effects on memory enhancement.
 
Luteolin can go through the blood-brain-barrier (BBB), which shows anti-amnesic effects against the toxicity of amyloid in mice.
 
In an experiment on rats with streptozotocin induced Alzheimer's disease, luteolin significantly improved spatial learning and memory impairment.
 
Luteolin also protects against high-fat diet-induced cognitive defects in obesity mice.
 
7) Luteolin is an Antiviral
 
Autoimmunity
 
Luteolin was found to have potent antiviral activity against Japanese encephalitis virus (JEV).
 
Luteolin reduced the number of Epstein-Barr virus reactivating cells and reduced the production of the virus. It does this by repressing the activities of the promoters of the immediate-early genes Zta and Rta.   
 
In mice with hepatitis B virus (HBV), Luteolin reduced HBV DNA replication, suggesting that it may be used for anti-HBV therapy.
 
8) Luteolin Prevents Cataracts
 
In rats, luteolin enhanced the antioxidant potential and lowered the oxidative damage to the lens' of rats in selenite-induced cataracts. It also improved the membrane integrity of the lens.
 
9) Luteolin May Be Therapeutic for Multiple Sclerosis
 
Multiple Sclerosis is a disease that affects the immune system - nerve damage causes pain and fatigue. Luteolin has anti-oxidant and anti-inflammatory effects which can reduce the effects of multiple sclerosis .
 
10) Luteolin Inhibits Mast Cells
 
Luteolin inhibits mast cells and mast cell-dependent T cell activation, factors which contribute to multiple sclerosis .
 
In this way, it can also help with histamine intolerance.
 
11) Luteolin Has Anti-Depressant Effects
 
The endoplasmic reticulum in a cell can undergo stress, which can cause cell death. In the brain, neuronal cells undergo cell death and this can cause symptoms of depression.
 
Luteolin significantly suppresses cell death by relieving endoplasmic reticulum stress.