Quality Pharmaceutical Raw Material Tacrolimus CAS 104987-11-3

Model NO.: Tacrolimus CAS 104987-11-3
Specification: 10cmx10comx10cm
Origin: Hubei
Model NO.: Tacrolimus CAS 104987-11-3
Specification: 10cmx10comx10cm
Origin: Hubei

Quality Pharmaceutical Raw Material Tacrolimus CAS 104987-11-3


Injectable Contraceptive Prohormones Steroids Medroxyprogesterone 17- Acetate 71-58-9
Basic information

Basic info.

Tacrolimus
Purity: 99%
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Melting Point: 113-115° C
Boiling Point: 871.7 ° C at 760 mmHg
Appearance: White powder
Lead time: 1-2 days upon receipt of payment
Delivery time: Usually 4-6 working days by air
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
 
Description
 
1. Tacrolimus is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response.
 
2. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.
Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.
 
3. Chemically it is a 23-membered macrolide lactone that was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.

Application

Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.
 
 

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Lyophilized Peptide 
Name CAS No. Specification  Name CAS No. Specification 
    0.5mg/vial
1mg/vial
2mg/vial
5mg/vial
10mg/vial
Oxytocin 50-56-6 2mg/vial
MTII 121062-08-6 5mg/vial
10mg/vial
Thymosin α1 Acetate 62304-98-7 10mg/vial
MTI 75921-69-6 5mg/vial
10mg/vial
PEG-MGF   2mg/vial
ipamorelin 170851-70-4 1mg/vial
2mg/vial
5mg/vial
10mg/vial
ACE 031   1mg/vial
CJC-1295 863288-34-0 2mg/vial
5mg/vial
10mg/vial
AOD-9604 221231-10-3 2mg/vial
CJC-1295DAC   2mg/vial
5mg/vial
10mg/vial
PT141 32780-32-8 10mg/vial
Hexarelin 140703-51-1 2mg/vial Follistatin 315   1mg/vial
  946870-92-4 0.1mg/vial
1mg/vial
Follistatin 344   1mg/vial
pentadecapeptide BPC 157 137525-51-0 2mg/vial
5mg/vial
GDF-8   1mg/vial
GHRP-2 158861-67-7 5mg/vial
10mg/vial
Gonadorelin 34973-08-5 2mg/vial
5mg/vial
10mg/vial
GHRP-6 87616-84-0 5mg/vial
10mg/vial
sermorelin 86168-78-7 2mg/vial
Epitalon 307297-39-8 10mg/vial DSIP 62568-57-4 2mg/vial
TB500 75591-33-4 2mg/vial
5mg/vial
dermorphin   10mg/vial
MGF   2mg/vial
5mg/vial
Argireline Acetate 616204-22-9 5mg/vial
Deslorelin 57773-65-6 20mg/vial     1000IU per vial
5000IU per vial
Selank   5mg/vial Tesamorelin 218949-48-5 2mg/vial

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