[Artifact attack] Small bioreactor that can produce life-saving drugs anytime, anywhere

In remote areas of the world, it is difficult to get those who need it to get vital medicines, so researchers in the United States have developed a small portable bioreactor that can produce anywhere. a drug.

By adding a mixture of various acids and cell extracts to the reactor, it produces the protein you need to treat diabetes, anemia, and various infections, and it is more efficient than today's commercial equipment. The team at Oak Ridge National Laboratory said: "We found that by promoting the exchange of small molecules in this two-tube bioreactor, this micro-bioreactor is designed to produce higher yields than traditional tube cultures."

In the middle of the small bioreactor are two tightly wound, 4.9 m long pipes that have been etched into a tiny porous silica membrane. The reaction takes place in one of the pipes, and the protein then enters another pipe through a special membrane so that people can exchange metabolic molecules, energy and species exchanges to inhibit protein production in other ways, but one can pass through the reactor. Membrane and serpentine pipes are used for control.

Although there is still a long way to go before researchers bring this device to the market, people who live in remote areas will also enjoy important treatments. The team has not yet fully evaluated the cost of such a bioreactor, but they think it is much cheaper than existing solutions anyway.

[Artifact attack] Small bioreactor that can produce life-saving drugs anytime, anywhere

The most different thing about the new method is that when it comes to producing the protein it needs, people don't have to guarantee the activity of the organic material, which makes long-distance transportation and long-term storage easier. Soldiers stationed away from the city can also use this technology to treat various diseases. (The US military agency DARPA also sponsored some funding for this research).

Finally, such devices may also produce drugs that are temporarily in short supply or that are prohibitively expensive. Another use of the bioreactor is to establish a medical channel and infrastructure that has collapsed in the desert.

The main author of the study, Scott Retterer, said: "With this approach, we are able to produce proteins faster and make our technology more suitable for medical sites. In fact, this cell-free production reduces the basics needed to produce protein. Facility requirements bypass the challenge of cryogenic refrigeration when transporting and storing proteins."

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