LONDON, November 2 — Researchers from around the world have revealed in a study published in the prestigious journal *Nature Genetics* that two specific genetic variations could significantly raise the risk of lung cancer by as much as 60%. The findings, based on data from over 15,000 participants across 18 countries, offer new insights into the hereditary factors behind this deadly disease.
The research involved 6,000 lung cancer patients and 9,000 individuals without the condition. Scientists analyzed their genetic profiles and discovered that mutations in two genes — TERT and CRR9 — located on chromosome 5, may play a key role in increasing susceptibility to lung cancer. While smoking remains the primary known cause, the study highlights that genetics could explain why some long-term smokers never develop the disease, while others who have never smoked do.
According to the American Cancer Society, lung cancer is the leading cause of cancer-related deaths among men globally and the second most common cause of cancer death among women. These findings underscore the need for further research into genetic risk factors, which could lead to better prevention strategies and personalized treatments in the future.
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